Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

Although death receptors and chemotherapeutic drugs activate distinct apoptosis signaling cascades, crosstalk between the extrinsic and intrinsic apoptosis pathway has been recognized as an important amplification mechanism. Best known in this regard is the amplification of the Fas (CD95) signal in...

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Detalhes bibliográficos
Main Authors: Schneider-Jakob, S, Corazza, N, Badmann, A, Sidler, D, Stuber-Roos, R, Keogh, A, Frese, S, Tschan, M, Brunner, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035907/
https://ncbi.nlm.nih.gov/pubmed/21368859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.66
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