Functional Screening of Alzheimer Pathology Genome-wide Association Signals in Drosophila

We have leveraged a Drosophila model relevant to Alzheimer disease (AD) for functional screening of findings from a genome-wide scan for loci associated with a quantitative measure of AD pathology in humans. In six of the 15 genomic regions evaluated, we successfully identified a causal gene for the...

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Detaylı Bibliyografya
Asıl Yazarlar: Shulman, Joshua M., Chipendo, Portia, Chibnik, Lori B., Aubin, Cristin, Tran, Dong, Keenan, Brendan T., Kramer, Patricia L., Schneider, Julie A., Bennett, David A., Feany, Mel B., De Jager, Philip L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2011
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035702/
https://ncbi.nlm.nih.gov/pubmed/21295279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.01.006
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