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Genetic modifiers of tauopathy in Drosophila.

In Alzheimer's disease and related disorders, the microtubule-associated protein Tau is abnormally hyperphosphorylated and aggregated into neurofibrillary tangles. Mutations in the tau gene cause familial frontotemporal dementia. To investigate the molecular mechanisms responsible for Tau-induc...

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Detalles Bibliográficos
Main Authors: Shulman, Joshua M, Feany, Mel B
Formato: Artigo
Idioma:Inglês
Publicado: 2003
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462852/
https://ncbi.nlm.nih.gov/pubmed/14668378
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