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Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model
Mitochondrial and metabolic dysfunction are often implicated in neurological disease, but effective mechanism-based therapies remain elusive. We performed a genome-scale forward genetic screen in a Drosophila model of tauopathy, a class of neurodegenerative disorders characterized by the accumulatio...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7777082/ https://ncbi.nlm.nih.gov/pubmed/33318181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922392117 |
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