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Strategies For The Rapid Construction Of Conditionally-Replicating HSV-1 Vectors Expressing Foreign Genes As Anti-Cancer Therapeutic Agents

Conditionally replication-competent Herpes Simplex Virus Type 1 (HSV-1) vectors expressing foreign genes have been developed as experimental therapeutic agents. Traditional methods of virus construction, including growth selection based on thymidine kinase gene expression, and color selection based...

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Detalhes bibliográficos
Main Authors: Parker, Jacqueline N., Zheng, Xiaojia, Luckett, William, Markert, James M., Cassady, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034828/
https://ncbi.nlm.nih.gov/pubmed/21142023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100230y
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