HIV-1(89.6) Gag Expressed from a Replication Competent HSV-1 Vector Elicits Persistent Cellular Immune Responses in Mice

We have constructed a replication competent, γ(1)34.5-deleted Herpes Simplex Virus type 1 (HSV-1) vector (J200) that expresses the gag gene from Human Immunodeficiency Virus type-1, primary isolate 89.6 (HIV-1(89.6)), as a candidate vaccine for HIV-1. J200 replicates in vitro, resulting in abundant...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Parker, Scott D., Rottinghaus, Scott T., Zajac, Allan J., Yue, Ling, Hunter, Eric, Whitley, Richard J., Parker, Jacqueline N.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084203/
https://ncbi.nlm.nih.gov/pubmed/17706843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.06.064
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