Multiple tissues express alpha 1-antitrypsin in transgenic mice and man.

Hepatocytes are considered to be the predominant source of alpha 1-antitrypsin (AAT), the major antiprotease in human plasma. The development of emphysema in the hereditary PiZ AAT deficiency state suggests that inhibition of leukocyte elastase in the lung is a major function of this protein. In add...

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Main Authors: Carlson, J A, Rogers, B B, Sifers, R N, Hawkins, H K, Finegold, M J, Woo, S L
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC303472/
https://ncbi.nlm.nih.gov/pubmed/3260605
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