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Multiple tissues express alpha 1-antitrypsin in transgenic mice and man.
Hepatocytes are considered to be the predominant source of alpha 1-antitrypsin (AAT), the major antiprotease in human plasma. The development of emphysema in the hereditary PiZ AAT deficiency state suggests that inhibition of leukocyte elastase in the lung is a major function of this protein. In add...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1988
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC303472/ https://ncbi.nlm.nih.gov/pubmed/3260605 |
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