Multiple tissues express alpha 1-antitrypsin in transgenic mice and man.
Hepatocytes are considered to be the predominant source of alpha 1-antitrypsin (AAT), the major antiprotease in human plasma. The development of emphysema in the hereditary PiZ AAT deficiency state suggests that inhibition of leukocyte elastase in the lung is a major function of this protein. In add...
Збережено в:
| Опубліковано в:: | J Clin Invest |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Clinical Investigation
1988
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3260605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113580 |
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