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γ-Secretase-dependent amyloid-β is increased in Niemann-Pick type C: A cross-sectional study
OBJECTIVE: Niemann-Pick disease type C (NPC) is an inherited disorder characterized by intracellular accumulation of lipids such as cholesterol and glycosphingolipids in endosomes and lysosomes. This accumulation induces progressive degeneration of the nervous system. NPC shows some intriguing simil...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Lippincott Williams & Wilkins
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034414/ https://ncbi.nlm.nih.gov/pubmed/21205675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318208f4ab |
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