Leptin Regulates Amyloid β Production Via the γ-Secretase Complex

Alzheimer’s Disease (AD) is the most common age-related neurodegenerative disease, affecting an estimated 5.3 million people in the United States. While many factors likely contribute to AD progression, it is widely accepted that AD is driven by the accumulation of β-amyloid (Aβ), a small, fibrillog...

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Detalhes bibliográficos
Main Authors: Niedowicz, Dana M., Studzinski, Christa M., Weidner, Adam M., Platt, Thomas L., Kingry, Kristen N., Beckett, Tina L., Bruce-Keller, Annadora J., Keller, Jeffrey N., Murphy, M. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557588/
https://ncbi.nlm.nih.gov/pubmed/23274884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.12.009
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