Leptin Regulates Amyloid β Production Via the γ-Secretase Complex

Alzheimer’s Disease (AD) is the most common age-related neurodegenerative disease, affecting an estimated 5.3 million people in the United States. While many factors likely contribute to AD progression, it is widely accepted that AD is driven by the accumulation of β-amyloid (Aβ), a small, fibrillog...

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Hauptverfasser: Niedowicz, Dana M., Studzinski, Christa M., Weidner, Adam M., Platt, Thomas L., Kingry, Kristen N., Beckett, Tina L., Bruce-Keller, Annadora J., Keller, Jeffrey N., Murphy, M. Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557588/
https://ncbi.nlm.nih.gov/pubmed/23274884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.12.009
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