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Leptin Regulates Amyloid β Production Via the γ-Secretase Complex

Alzheimer’s Disease (AD) is the most common age-related neurodegenerative disease, affecting an estimated 5.3 million people in the United States. While many factors likely contribute to AD progression, it is widely accepted that AD is driven by the accumulation of β-amyloid (Aβ), a small, fibrillog...

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Bibliografske podrobnosti
Main Authors: Niedowicz, Dana M., Studzinski, Christa M., Weidner, Adam M., Platt, Thomas L., Kingry, Kristen N., Beckett, Tina L., Bruce-Keller, Annadora J., Keller, Jeffrey N., Murphy, M. Paul
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557588/
https://ncbi.nlm.nih.gov/pubmed/23274884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.12.009
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