Circulating Neprilysin Clears Brain Amyloid

The use of the peptidase neprilysin (NEP) as a therapeutic for lowering brain amyloid burden is receiving increasing attention. We have previously demonstrated that peripheral expression of NEP on the surface of hindlimb muscle lowers brain amyloid burden in a transgenic mouse model of Alzheimer’s d...

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Bibliographic Details
Main Authors: Liu, Yinxing, Studzinski, Christa, Beckett, Tina, Murphy, M. Paul, Klein, Ronald L., Hersh, Louis B.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923273/
https://ncbi.nlm.nih.gov/pubmed/20558294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.05.014
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