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Peripherally expressed neprilysin reduces brain amyloid burden: A novel approach for treating Alzheimer’s disease

A number of therapeutic strategies for treating Alzheimer’s disease have focused on reducing amyloid burden in the brain. Amongst these approaches, the expression of amyloid β peptide (Aβ)-degrading enzymes in the brain has been shown to be effective, but to date not practical for treating patients....

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Détails bibliographiques
Auteurs principaux: Guan, Hanjun, Liu, Yinxing, Daily, Abigail, Police, Sara, Kim, Myung-Hee, Oddo, Salvatore, LaFerla, Frank M., Pauly, James R., Murphy, M. Paul, Hersh, Louis B.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832596/
https://ncbi.nlm.nih.gov/pubmed/19021293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21944
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