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The Alzheimer's Amyloid-Degrading Peptidase, Neprilysin: Can We Control It?
The amyloid cascade hypothesis of Alzheimer's disease (AD) postulates that accumulation in the brain of amyloid β-peptide (Aβ) is the primary trigger for neuronal loss specific to this pathology. In healthy brain, Aβ levels are regulated by a dynamic equilibrium between Aβ release from the amyl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412116/ https://ncbi.nlm.nih.gov/pubmed/22900228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/383796 |
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