Amyloid β-Peptide and Oligomers in the Brain and CSF of Aged Canines

The study of Alzheimer’s disease (AD) pathogenesis requires the use of animal models that develop some amount of amyloid pathology in the brain. Aged canines (beagles) naturally accumulate human-type amyloid β-peptide (Aβ) and develop parallel declines in cognitive function. However, the type and qu...

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Detalhes bibliográficos
Main Authors: Head, Elizabeth, Pop, Viorela, Sarsoza, Floyd, Kayed, Rakez, Beckett, Tina L., Studzinski, Christa M., Tomic, Jennifer L., Glabe, Charles G., Murphy, M. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903832/
https://ncbi.nlm.nih.gov/pubmed/20164551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1397
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