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Amyloid β-Peptide and Oligomers in the Brain and CSF of Aged Canines

The study of Alzheimer’s disease (AD) pathogenesis requires the use of animal models that develop some amount of amyloid pathology in the brain. Aged canines (beagles) naturally accumulate human-type amyloid β-peptide (Aβ) and develop parallel declines in cognitive function. However, the type and qu...

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Autors principals: Head, Elizabeth, Pop, Viorela, Sarsoza, Floyd, Kayed, Rakez, Beckett, Tina L., Studzinski, Christa M., Tomic, Jennifer L., Glabe, Charles G., Murphy, M. Paul
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903832/
https://ncbi.nlm.nih.gov/pubmed/20164551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1397
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