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Amyloid β-Peptide and Oligomers in the Brain and CSF of Aged Canines
The study of Alzheimer’s disease (AD) pathogenesis requires the use of animal models that develop some amount of amyloid pathology in the brain. Aged canines (beagles) naturally accumulate human-type amyloid β-peptide (Aβ) and develop parallel declines in cognitive function. However, the type and qu...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903832/ https://ncbi.nlm.nih.gov/pubmed/20164551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1397 |
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