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Oxidative Stress in Niemann-Pick Disease, Type C

Niemann-Pick Disease, type C (NPC) is a neurodegenerative lysosomal storage disorder due to impaired intracellular cholesterol and lipid transport. Increased oxidative stress has been reported in human NPC1 mutant fibroblasts and in tissues from Npc1 mutant mice. However, oxidative stress in NPC pat...

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Detalhes bibliográficos
Main Authors: Fu, Rao, Yanjanin, Nicole M., Bianconi, Simona, Pavan, William J., Porter, Forbes D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950258/
https://ncbi.nlm.nih.gov/pubmed/20667755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2010.06.018
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