p50α/p55α Phosphoinositide 3-Kinase Knockout Mice Exhibit Enhanced Insulin Sensitivity

Class Ia phosphoinositide (PI) 3-kinases are heterodimers composed of a regulatory and a catalytic subunit and are essential for the metabolic actions of insulin. In addition to p85α and p85β, insulin-sensitive tissues such as fat, muscle, and liver express the splice variants of the pik3r1 gene, p5...

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Detalhes bibliográficos
Main Authors: Chen, Dong, Mauvais-Jarvis, Franck, Bluher, Matthias, Fisher, Simon J., Jozsi, Alison, Goodyear, Laurie J., Ueki, Kohjiro, Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303335/
https://ncbi.nlm.nih.gov/pubmed/14673165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.320-329.2004
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