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p50α/p55α Phosphoinositide 3-Kinase Knockout Mice Exhibit Enhanced Insulin Sensitivity

Class Ia phosphoinositide (PI) 3-kinases are heterodimers composed of a regulatory and a catalytic subunit and are essential for the metabolic actions of insulin. In addition to p85α and p85β, insulin-sensitive tissues such as fat, muscle, and liver express the splice variants of the pik3r1 gene, p5...

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Udgivet i:Mol Cell Biol
Principais autores: Chen, Dong, Mauvais-Jarvis, Franck, Bluher, Matthias, Fisher, Simon J., Jozsi, Alison, Goodyear, Laurie J., Ueki, Kohjiro, Kahn, C. Ronald
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303335/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.320-329.2004
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