Virtual Ligand Screening of the National Cancer Institute (NCI) Compound Library Leads to the Allosteric Inhibitory Scaffolds of the West Nile Virus NS3 Proteinase

Viruses of the genus Flavivirus are responsible for significant human disease and mortality. The N-terminal domain of the flaviviral nonstructural (NS)3 protein codes for the serine, chymotrypsin-fold proteinase (NS3pro). The presence of the nonstructural (NS)2B cofactor, which is encoded by the ups...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Shiryaev, Sergey A., Cheltsov, Anton V., Gawlik, Katarzyna, Ratnikov, Boris I., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2011
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033206/
https://ncbi.nlm.nih.gov/pubmed/21050032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0309
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares