DNA Oligomers Containing Site- and Stereospecific Exocyclic Deoxyadenosine Adducts of 1,2,3,4-Diepoxybutane: Synthesis, Characterization, and Effects on DNA Structure

1,2,3,4-Diepoxybutane (DEB) is a carcinogenic metabolite of 1,3-butadiene (BD), an important industrial and environmental chemical present in urban air and in cigarette smoke. DEB is considered the ultimate carcinogenic species of BD due to its potent genotoxicity and mutagenicity attributed to its...

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Bibliografiska uppgifter
Huvudupphovsmän: Seneviratne, Uthpala, Antsypovich, Sergey, Dorr, Danae Quirk, Dissanayake, Thakshila, Kotapati, Srikanth, Tretyakova, Natalia
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032033/
https://ncbi.nlm.nih.gov/pubmed/20873715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100146v
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