Lanean...
Structural basis for human PHF2 Jumonji domain interaction with metal ions
PHF2 belongs to a class of α-ketoglutarate-Fe(2+)–dependent dioxygenases. PHF2 harbors a plant homeodomain (PHD) and a Jumonji domain. PHF2, via its PHD domain, binds Lys4-trimethylated histone 3 (H3K4me3) in sub micromolar affinity, and has been reported to have demethylase activity of mono-methyla...
Gorde:
| Egile Nagusiak: | , , , , |
|---|---|
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030633/ https://ncbi.nlm.nih.gov/pubmed/21167174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.013 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|