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Coordinated Methyl-lysine Erasure: Structural and Functional Linkage of a Jumonji demethylasedomain and a Reader domain
Both components of chromatin (DNA and histones) are subjected to dynamic post-synthetic covalent modifications. Dynamic histone lysine methylation involves the activities of modifying enzymes (writers), enzymes removing modifications (erasers), and readers of the epigenetic code. Known histone lysin...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232282/ https://ncbi.nlm.nih.gov/pubmed/21872465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.08.003 |
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