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Coordinated Methyl-lysine Erasure: Structural and Functional Linkage of a Jumonji demethylasedomain and a Reader domain

Both components of chromatin (DNA and histones) are subjected to dynamic post-synthetic covalent modifications. Dynamic histone lysine methylation involves the activities of modifying enzymes (writers), enzymes removing modifications (erasers), and readers of the epigenetic code. Known histone lysin...

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Main Authors: Upadhyay, Anup K., Horton, John R., Zhang, Xing, Cheng, Xiaodong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232282/
https://ncbi.nlm.nih.gov/pubmed/21872465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.08.003
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