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HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developmental Regulatory Role for a Housekeeping Gene?

We have used microarray-based methods of global gene expression together with quantitative PCR and Western blot analysis to identify dysregulation of genes and aberrant cellular processes in human fibroblasts and in SH-SY5Y neuroblastoma cells made HPRT-deficient by transduction with a retrovirus st...

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Hlavní autoři: Kang, Tae Hyuk, Guibinga, Ghiabe-Henri, Friedmann, Theodore
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030599/
https://ncbi.nlm.nih.gov/pubmed/21305049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016572
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