Loading...

HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developmental Regulatory Role for a Housekeeping Gene?

We have used microarray-based methods of global gene expression together with quantitative PCR and Western blot analysis to identify dysregulation of genes and aberrant cellular processes in human fibroblasts and in SH-SY5Y neuroblastoma cells made HPRT-deficient by transduction with a retrovirus st...

Full description

Saved in:
Bibliographic Details
Main Authors: Kang, Tae Hyuk, Guibinga, Ghiabe-Henri, Friedmann, Theodore
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030599/
https://ncbi.nlm.nih.gov/pubmed/21305049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016572
Tags: Add Tag
No Tags, Be the first to tag this record!