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Human DNA Polymerase β Mutations Allowing Efficient Abasic Site Bypass
The DNA of every cell in the human body gets damaged more than 50,000 times a day. The most frequent damages are abasic sites. This kind of damage blocks proceeding DNA synthesis by several DNA polymerases that are involved in DNA replication and repair. The mechanistic basis for the incapability of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030401/ https://ncbi.nlm.nih.gov/pubmed/21107011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176826 |
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