Replication through an abasic DNA lesion: structural basis for adenine selectivity

Abasic sites represent the most frequent DNA lesions in the genome that have high mutagenic potential and lead to mutations commonly found in human cancers. Although these lesions are devoid of the genetic information, adenine is most efficiently inserted when abasic sites are bypassed by DNA polyme...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Obeid, Samra, Blatter, Nina, Kranaster, Ramon, Schnur, Andreas, Diederichs, Kay, Welte, Wolfram, Marx, Andreas
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2010
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876968/
https://ncbi.nlm.nih.gov/pubmed/20400942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.64
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים