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Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase
Numerous 2′-deoxynucleoside triphosphates (dNTPs) that are functionalized with spacious modifications such as dyes and affinity tags like biotin are substrates for DNA polymerases. They are widely employed in many cutting-edge technologies like advanced DNA sequencing approaches, microarrays, and si...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003043/ https://ncbi.nlm.nih.gov/pubmed/21123743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013804107 |
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