Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans

Understanding the entry of autoreactive T cells to their target organ is important in autoimmunity because this entry initiates the inflammatory process. Here, the events that lead to specific localization of diabetogenic CD4 T cells into islets of Langerhans resulting in diabetes were examined. Thi...

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Bibliographic Details
Main Authors: Calderon, Boris, Carrero, Javier A., Miller, Mark J., Unanue, Emil R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029745/
https://ncbi.nlm.nih.gov/pubmed/21220322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018973108
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