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Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules

Islets of Langerhans from normal mice contained dendritic cells (DCs) in the range of 8–10 per islet. DCs were found in several mouse strains, including those from lymphocyte-deficient mice. DCs were absent in islets from colony stimulating factor-1 deficient mice and this absence correlated with sm...

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Detalhes bibliográficos
Main Authors: Calderon, Boris, Suri, Anish, Miller, Mark J., Unanue, Emil R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329714/
https://ncbi.nlm.nih.gov/pubmed/18427107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801973105
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