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Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response

In an accompanying paper, we find specific localization of diabetogenic T cells only to islets of Langerhans bearing the specific antigen. Instrumental in the specific localization was the presence of intraislet dendritic cells bearing the β-cell-peptide-MHC complex. Here, we report that the entry o...

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Bibliografiske detaljer
Main Authors: Calderon, Boris, Carrero, Javier A., Miller, Mark J., Unanue, Emil R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029718/
https://ncbi.nlm.nih.gov/pubmed/21220309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018975108
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