Characterization of the Betaherpesviral pUL69 Protein Family Reveals Binding of the Cellular mRNA Export Factor UAP56 as a Prerequisite for Stimulation of Nuclear mRNA Export and for Efficient Viral Replication

UL69 of human cytomegalovirus (HCMV) encodes a pleiotropic transactivator protein and has a counterpart in every member of the Herpesviridae family thus far sequenced. However, little is known about the conservation of the functions of the nuclear phosphoprotein pUL69 in the homologous proteins of o...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zielke, Barbara, Thomas, Marco, Giede-Jeppe, Antje, Müller, Regina, Stamminger, Thomas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2011
Θέματα:
Genome Replication and Regulation of Viral Gene Expression
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028876/
https://ncbi.nlm.nih.gov/pubmed/21147923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01347-10
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