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Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice
OBJECTIVE: To determine the role of glucagon action in the metabolic phenotype of untreated insulin deficiency. RESEARCH DESIGN AND METHODS: We compared pertinent clinical and metabolic parameters in glucagon receptor-null (Gcgr(−/−)) mice and wild-type (Gcgr(+/+)) controls after equivalent destruct...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Diabetes Association
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028337/ https://ncbi.nlm.nih.gov/pubmed/21270251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0426 |
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