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Hypoglycemia, hyperglucagonemia, and fetoplacental defects in glucagon receptor knockout mice: a role for glucagon action in pregnancy maintenance

Alterations in insulin signaling as well as insulin action predispose to infertility as well as adverse pregnancy outcomes; however, little is known about the role of glucagon signaling in reproduction. The glucagon receptor knockout (Gcgr(−/−)) mouse created by our laboratory was used to define the...

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Detalhes bibliográficos
Main Authors: Ouhilal, Sophia, Vuguin, Patricia, Cui, Lingguang, Du, Xiu-Quan, Gelling, Richard W., Reznik, Sandra E., Russell, Robert, Parlow, Albert F., Karpovsky, Clara, Santoro, Nanette, Charron, Maureen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311287/
https://ncbi.nlm.nih.gov/pubmed/22167521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00420.2011
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