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Novel insight into glucagon receptor action: lessons from knockout and transgenic mouse models
Using knockout and transgenic technology, genetically modified animal models allowed us to understand the role of glucagon signalling in metabolism. Mice with a global deletion of the glucagon receptor gene (Gcgr) were designed using gene targeting. The phenotype of Gcgr(−/−) mouse provided importan...
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| Publicado no: | Diabetes Obes Metab |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287250/ https://ncbi.nlm.nih.gov/pubmed/21824268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2011.01447.x |
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