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Novel insight into glucagon receptor action: lessons from knockout and transgenic mouse models

Using knockout and transgenic technology, genetically modified animal models allowed us to understand the role of glucagon signalling in metabolism. Mice with a global deletion of the glucagon receptor gene (Gcgr) were designed using gene targeting. The phenotype of Gcgr(−/−) mouse provided importan...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Diabetes Obes Metab
Main Authors: Vuguin, P. M., Charron, M. J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287250/
https://ncbi.nlm.nih.gov/pubmed/21824268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2011.01447.x
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