Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice

Ventricular preexcitation, a feature of Wolff-Parkinson-White syndrome, is caused by accessory myocardial pathways that bypass the annulus fibrosus. This condition increases the risk of atrioventricular tachycardia and, in the presence of atrial fibrillation, sudden death. The developmental mechanis...

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Autori principali: Aanhaanen, Wim T.J., Boukens, Bastiaan J.D., Sizarov, Aleksander, Wakker, Vincent, de Gier-de Vries, Corrie, van Ginneken, Antoni C., Moorman, Antoon F.M., Coronel, Ruben, Christoffels, Vincent M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026729/
https://ncbi.nlm.nih.gov/pubmed/21266775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44350
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