Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation

During heart development, chamber myocardium forms locally from the embryonic myocardium of the tubular heart. The atrial natriuretic factor (ANF) gene is specifically expressed in this developing chamber myocardium and is one of the first hallmarks of chamber formation. We investigated the regulato...

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Detalhes bibliográficos
Main Authors: Habets, Petra E.M.H., Moorman, Antoon F.M., Clout, Danielle E.W., van Roon, Marian A., Lingbeek, Merel, van Lohuizen, Maarten, Campione, Marina, Christoffels, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186286/
https://ncbi.nlm.nih.gov/pubmed/12023302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.222902
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