Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

The sinoatrial node initiates the heartbeat and controls the rate and rhythm of contraction, thus serving as the pacemaker of the heart. Despite the crucial role of the sinoatrial node in heart function, the mechanisms that underlie its specification and formation are not known. Tbx3, a transcriptio...

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Hlavní autoři: Hoogaars, Willem M.H., Engel, Angela, Brons, Janynke F., Verkerk, Arie O., de Lange, Frederik J., Wong, L.Y. Elaine, Bakker, Martijn L., Clout, Danielle E., Wakker, Vincent, Barnett, Phil, Ravesloot, Jan Hindrik, Moorman, Antoon F.M., Verheijck, E. Etienne, Christoffels, Vincent M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855235/
https://ncbi.nlm.nih.gov/pubmed/17473172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.416007
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