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Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis

The 22q11.2 deletion syndrome (22q11.2DS) is the most common microdeletion disorder and is characterized by abnormal development of the pharyngeal apparatus and heart. Cardiovascular malformations (CVMs) affecting the outflow tract (OFT) are frequently observed in 22q11.2DS and are among the most co...

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Detalhes bibliográficos
Main Authors: Mesbah, Karim, Rana, M. Sameer, Francou, Alexandre, van Duijvenboden, Karel, Papaioannou, Virginia E., Moorman, Antoon F., Kelly, Robert G., Christoffels, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491916/
https://ncbi.nlm.nih.gov/pubmed/22116936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr553
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