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Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis

The 22q11.2 deletion syndrome (22q11.2DS) is the most common microdeletion disorder and is characterized by abnormal development of the pharyngeal apparatus and heart. Cardiovascular malformations (CVMs) affecting the outflow tract (OFT) are frequently observed in 22q11.2DS and are among the most co...

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Autori principali: Mesbah, Karim, Rana, M. Sameer, Francou, Alexandre, van Duijvenboden, Karel, Papaioannou, Virginia E., Moorman, Antoon F., Kelly, Robert G., Christoffels, Vincent M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491916/
https://ncbi.nlm.nih.gov/pubmed/22116936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr553
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