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Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production

Main Escherichia coli cytosolic chaperones such as DnaK are key components of the control quality network designed to minimize the prevalence of polypeptides with aberrant conformations. This is achieved by both favoring refolding activities but also stimulating proteolytic degradation of folding re...

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Detalhes bibliográficos
Main Authors: Martínez-Alonso, Mónica, Villaverde, Antonio, Ferrer-Miralles, Neus
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026456/
https://ncbi.nlm.nih.gov/pubmed/21326941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.2.11048
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