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Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production

Main Escherichia coli cytosolic chaperones such as DnaK are key components of the control quality network designed to minimize the prevalence of polypeptides with aberrant conformations. This is achieved by both favoring refolding activities but also stimulating proteolytic degradation of folding re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martínez-Alonso, Mónica, Villaverde, Antonio, Ferrer-Miralles, Neus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026456/
https://ncbi.nlm.nih.gov/pubmed/21326941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.2.11048
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