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Cross-system excision of chaperone-mediated proteolysis in chaperone-assisted recombinant protein production

Main Escherichia coli cytosolic chaperones such as DnaK are key components of the control quality network designed to minimize the prevalence of polypeptides with aberrant conformations. This is achieved by both favoring refolding activities but also stimulating proteolytic degradation of folding re...

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Autors principals: Martínez-Alonso, Mónica, Villaverde, Antonio, Ferrer-Miralles, Neus
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026456/
https://ncbi.nlm.nih.gov/pubmed/21326941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.2.11048
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