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Microbial factories for recombinant pharmaceuticals

Most of the hosts used to produce the 151 recombinant pharmaceuticals so far approved for human use by the Food and Drug Administration (FDA) and/or by the European Medicines Agency (EMEA) are microbial cells, either bacteria or yeast. This fact indicates that despite the diverse bottlenecks and obs...

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Detalhes bibliográficos
Main Authors: Ferrer-Miralles, Neus, Domingo-Espín, Joan, Corchero, José Luis, Vázquez, Esther, Villaverde, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669800/
https://ncbi.nlm.nih.gov/pubmed/19317892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-8-17
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