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Intracellular CXCR4(+) cell targeting with T22-empowered protein-only nanoparticles

BACKGROUND: Cell-targeting peptides or proteins are appealing tools in nanomedicine and innovative medicines because they increase the local drug concentration and reduce potential side effects. CXC chemokine receptor 4 (CXCR4) is a cell surface marker associated with several severe human pathologie...

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Detalhes bibliográficos
Main Authors: Unzueta, Ugutz, Céspedes, María Virtudes, Ferrer-Miralles, Neus, Casanova, Isolda, Cedano, Juan, Corchero, José Luis, Domingo-Espín, Joan, Villaverde, Antonio, Mangues, Ramón, Vázquez, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423154/
https://ncbi.nlm.nih.gov/pubmed/22923991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S34450
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