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Side effects of chaperone gene co-expression in recombinant protein production

Insufficient availability of molecular chaperones is observed as a major bottleneck for proper protein folding in recombinant protein production. Therefore, co-production of selected sets of cell chaperones along with foreign polypeptides is a common approach to increase the yield of properly folded...

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Detalhes bibliográficos
Main Authors: Martínez-Alonso, Mónica, García-Fruitós, Elena, Ferrer-Miralles, Neus, Rinas, Ursula, Villaverde, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944165/
https://ncbi.nlm.nih.gov/pubmed/20813055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-64
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