Inhibition of Lymphoid Tyrosine Phosphatase by Benzofuran Salicylic Acids

The lymphoid tyrosine phosphatase (Lyp, PTPN22) is a critical negative regulator of T cell antigen receptor (TCR) signaling. A single-nucleotide polymorphism (SNP) in the ptpn22 gene correlates with the incidence of various autoimmune diseases, including type 1 diabetes, rheumatoid arthritis, and sy...

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Hauptverfasser: Vang, Torkel, Xie, Yuli, Liu, Wallace H., Vidović, Dušica, Liu, Yidong, Wu, Shuangding, Smith, Deborah H., Rinderspacher, Alison, Chung, Caty, Gong, Gangli, Mustelin, Tomas, Landry, Donald W., Rickert, Robert C., Schürer, Stephan C., Deng, Shi-Xian, Tautz, Lutz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025750/
https://ncbi.nlm.nih.gov/pubmed/21190368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101004d
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