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Inhibition of Lymphoid Tyrosine Phosphatase by Benzofuran Salicylic Acids
The lymphoid tyrosine phosphatase (Lyp, PTPN22) is a critical negative regulator of T cell antigen receptor (TCR) signaling. A single-nucleotide polymorphism (SNP) in the ptpn22 gene correlates with the incidence of various autoimmune diseases, including type 1 diabetes, rheumatoid arthritis, and sy...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025750/ https://ncbi.nlm.nih.gov/pubmed/21190368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101004d |
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