Histone Deacetylase-3 antagonizes Aspirin-stimulated Endothelial Nitric Oxide production by reversing Aspirin-induced lysine acetylation of Endothelial Nitric Oxide Synthase

RATIONALE: Low-dose acetylsalicylic acid (aspirin) is widely used in the treatment and prevention of vascular atherothrombosis. Cardiovascular doses of aspirin also reduce systemic blood pressure and improve endothelium-dependent vasorelaxation in patients with atherosclerosis or risk factors for at...

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Autores principales: Jung, Saet-Byel, Kim, Cuk-Seong, Naqvi, Asma, Yamamori, Tohru, Mattagajasingh, Ilwola, Hoffman, Timothy A, Cole, Marsha P, Kumar, Ajay, DeRicco, Jeremy S., Jeon, Byeong Hwa, Irani, Kaikobad
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025612/
https://ncbi.nlm.nih.gov/pubmed/20705923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.222968
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