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Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases

Higher eukaryotes encode various Y-family DNA polymerases to perform global DNA lesion bypass. To provide complete mutation spectra for abasic lesion bypass, we employed short oligonucleotide sequencing assays to determine the sequences of abasic lesion bypass products synthesized by human Y-family...

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Auteurs principaux: Sherrer, Shanen M., Fiala, Kevin A., Fowler, Jason D., Newmister, Sean A., Pryor, John M., Suo, Zucai
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025555/
https://ncbi.nlm.nih.gov/pubmed/20846959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq719
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